Glutamate: Leader In Contemporary Translationa...

Anthropometric, Functional And Explosive Streng...

Systemic Sclerosis: A Case Report With Review

Clinicoseroepidemiological Evaluation Of Toxoc...

A Study Of Depression In Diabetes Mellitus: Ana...

0 votes
Molecular Depiction Of Lepa, Lida, Ralf, Rtxa And Lvhb Virulence Factors Of Legionella Pneumophila Isolated From Respiratory Tract Infections
Author: Forouzan Khedri, Fatemeh Alaei Faradonbeh, Mahvash Eliyasi, Anahita Barghi, Abbas Doosti, Pardis Emad, Aida Alaei Faradonbeh
Publisher: alaei faradonbeh fatemeh
11 pages
One time payment: €0.00
Required subscription: Free
Type of publication: Dissertation
Follow this publisher

Share this publication:


Background: Among all bacterial species in the genus Legionella, Legionella pneumophila is responsible for 90% of Legionella infec -tions in humans. Putative virulence genes are the main factors in pathogenesis of L. pneumophila . The aim of this study was to deter -mine the incidence of L. pneumophila in the broncho alveolar lavages of patients hospitalized due to respiratory tract infections as well as study the distribution of lepA , lidA , ralF , rtxA and lvhB virulence factors in bacterial strains.Methods: One hundred fifty BAL samples were collected from pa -tients who were referred to several Iranian health centers. Samples were cultured and those that were L. pneumophila positive were subjected to PCR method targeting the 16S rRNA gene. Samples positive for Legionella were analyzed for presence of latent virulence factors.Results: Thirteen out of 90 male BAL samples (14.4%) and 5 out of 60 female BAL samples (8.3%) were positive for L. pneumophila (P =0.046). Patients older than 50 years had the highest inciden -ce of L. pneumophila (20%), while patients younger than 15 years old had the lowest (4.16%) (P =0.017). All patients positive for L. pneumophila had fever, while the distribution of cough, dyspnea, chest pain and headache were 77.7%, 77.7%, 66.6% and 44.4%, respectively. The most commonly detected virulence factors among L. pneumophila isolates were lidA (50%) and ralF ( 2 7. 7 7 %) .Molecular Depiction Of lepa, lida, ralf, rt...

Select a payment method