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In contrast to its role as poison, hydrogen sulfide (H2S) is now considered as the third gaso transmitter after nitric oxide (NO) and carbon monoxide (CO) [1,2,3]. Though it was first reported in 1982 that they are produced in mammalian tissues, but it is only now emerged as a mediator of important physiologic functions in humans . In the central nervous system (CNS), H2S functions not only as a neuro-modulator, but also as a neuro-protectant against oxidative stress.
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