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Congenital Anomaly Of The Inferior Vena Cava And Factor V Leiden Mutation Predisposing To Deep Vein Thrombosis
Author: Lamparello Bm, Erickson Cr, Kulthia A, Virparia V, Thet Z
Publisher: Derivative Works
5 pages
One time payment: €0.00
Required subscription: Free
Type of publication: Article
ISBN/ISSN: 1178-2048
DOI: 10.2147/66283
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Abstract: A previously healthy 21-year-old man presented with back pain, bilateral extremity pain, and right lower extremity weakness, paresthesias, and swelling. Sonographic examination revealed diffuse deep vein thrombosis (DVT) in the femoral and popliteal venous system. CT imaging revealed hypoplasia of the hepatic inferior vena cava (IVC) segment with formation of multiple varices and collateral veins around the kidneys. Hematologic workup also discovered a factor V Leiden mutation, further predisposing the patient to DVT. The rare, often  verlooked occurrence of attenuated IVC, especially in the setting of hypercoagulable state, can predispose patients to significant thrombosis.

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