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Colistin In Critically Ill Patients: A Critical Review
Author: Jamal Wadi Al Ramahi , Abeer Al Bashaireh,samer Salman
Publisher: Internet Medical Publishing
15 pages
One time payment: €0.00
Required subscription: Free
Type of publication: Article
DOI: 4
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Description:

Colistin emerged in the last decade as a savior for the treatment of critically septic patients who suffer MDR-GNB infections.This development came in time with the drying new antibacterial pipelines. MDR- GNB became problematic in ICU’s including MDR Acinetobacter spp., Pseudomonas aeruginosa, and carbapenemase producing Enterobacteriaecae (CPE). With the resurgence of wide colistin prescription especially in ICU’s, awareness on when to switch to this reintroduced drug is required.

Recently, it is observed that there are differences between the past dosages and the currently proposed dosages. Nephrotoxicity and neurotoxicity are observed to be less than what was published in the past. This may be due to more pure preparations and attention to other drug therapies that are employed in the critically ill patients residing the ICU’s. However,randomized control studies are still lacking to shed light on its efficacy and safety. Agreement is still looming on dosages, and monotherapy of colistin versus its combination with other agents.

 

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iMedPub Limited is a publishing house registered in UK, publishing medical books and journals since 2005. As an open service to doctors and biomedical researchers, it is driven by clinicians and researchers for themselves, while serving the interests of the general public. iMedPub disseminates research in a tiered system, beginning with our specialty books and journals and then working upwards. The grand vision of iMedPub is a world where all medical researchers and health professionals have an equal opportunity to seek, share and create knowledge. As we are a low cost academic publisher we offer the lowest article processing charges of all biomedical journals and publish books free of charges for authors.

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