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Diabetes mellitus type 2 can be defied as a syndrome of multip etiologies and currently, it is estimated that in the world exists about 150 million patients with DM, and that number could double un 2025. Non-adherence to treatment is a diffiulty in effective assistance to individuals. This study aims to understand the factors related non-adherence to oral hypoglycemic drug in patients with type 2 mellitus diabetes It is an integrative review, held in the databases SciELOPubMed, MEDLINE and LILACS, using the descriptors DeCS (MeSH) Descriptors in Health Sciences: medication adherence, type 2 diabetes and chronic disease. The selection respected inclusion/exclusion criter previously listed considering the last six years. 108 articles of which 1 met the criteria were identifid. Among the factors that are related medication accession are: gender, age, education, income, information about the disease and the medication, comorbidities, side effects and the time of diagnosis. It become necessary in health education strategies to take into consideration the various personal differences.
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