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Paroxysmal Nocturnal Hemoglobinuria: Report Of Suboptimal Response To The Use Of Eculizumab
Author: Ricardo Parente Garcia Vieira, Lucas Parente Alencar, George Nilton Nunes Mendes, Natália Parente Alencar, Francisco Rômulo Patrício De Sá, Hermes Melo Teixeira Batista, Jully Graziela Coelho Campos Couto, José Lucas Souza Ramos, Thiáskara Rami
Publisher: Internet Medical Publishing
5 pages
One time payment: €0.00
Required subscription: Free
Type of publication: Article
DOI: 10.3823/1754
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Description:

The Paroxysmal Nocturnal Hemoglobinuria (PNH) is an acquired clonal disorder of one or more stem cells of hematopoietic lineage. It is characterized as a chronic hemolytic anemia in which there is a persistent intravascular hemolysis which is subject to exacerbations due to production of subpopulations of erythrocytes, platelets and granulocytes hypersensitive to complement. Furthermore there has been a high tendency to thrombosis. The anti-complement therapy is the only recognized treatment for this condition. We reporta case of PNH with suboptimal response to anti-complement therapy.

About the publisher:

iMedPub Limited is a publishing house registered in UK, publishing medical books and journals since 2005. As an open service to doctors and biomedical researchers, it is driven by clinicians and researchers for themselves, while serving the interests of the general public. iMedPub disseminates research in a tiered system, beginning with our specialty books and journals and then working upwards. The grand vision of iMedPub is a world where all medical researchers and health professionals have an equal opportunity to seek, share and create knowledge. As we are a low cost academic publisher we offer the lowest article processing charges of all biomedical journals and publish books free of charges for authors.

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