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Kaposi Sarcoma Pathogenesis: A Triad Of Viral Infection, Oncogenesis And Chronic Inflammation
Author: Janet L. Douglas, Jean K. Gustin, Ashlee V. Moses, Bruce J. Dezube, And Liron Pantanowitz
Publisher: Internet Medical Publishing
15 pages
One time payment: €0.00
Required subscription: Free
Type of publication: Article
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 Cellular hallmarks of KS progression include both the hyper proliferation of KSHV infected cells and the infiltration of immune modulatory cells into KS lesions, which together result in chronic inflammation, the induction of angiogenesis and tumor growth. This review describes the current understanding of the interactions between KSHV and host responses that result in this unusual cancer, along with existing treatments and prospects for future therapeutic approaches. 

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