Recommended

Bacillus Calmette-guerin Infection In Nadph Oxi...

Ive Effect Of N-acetylcystiene Against Titaniu...

Immunologic Special Forces: Anti-pathogen Cyto...

Energetic Levels Of Metabolic Pathways In Malig...

Salivary Carbonic Anhydrase Vi, Zinc Sulfate Ta...

0 votes
Actin Cytoskeleton And Related Proteins Role During Immune Cells Migration, Polarity And Activation: An Overview
Author: Claudio Vieira Da Silva
Publisher: Derivative Works
7 pages
One time payment: €0.00
Required subscription: Free
Type of publication: Article
ISBN/ISSN: 1553-619X
DOI: 10.3844/2013.132.138
Follow this publisher

Share this publication:

Description:

Immune cells migration, polarity and activation are essential during host immune response. Upon recognition of specific peptides presented by Human Leukocyte Antigen (HLA) molecules on Antigen Presenting Cells (APC), lymphocytes execute subset-related functions such as killing, help and regulation. These cells travel through the organism in a succession of steps, including entry into tissues, interstitial migration, APC scanning, synapse formation and tissue exit. Such ability is possible because of a plastic motility behavior, which is highly controlled in time and space. The scope of this review is to discuss recent data pointing to the key role of regulators of actin cytoskeleton remodeling in tuning migration, polarity and activation of immune cells during host immune response. We believe that the more complete understanding of actin and related proteins recruitment during these processes the better to obtain novel targets for establishing strategies to control immune responses.

About the publisher:

We are a publishing house devoted to reuse CC-BY licensed published materials.

 

Using CC-BY licenses:

YOU ARE FREE TO:

  • Adapt — remix, transform, and build upon the material
  • for any purpose, even commercially.
  • The licensor cannot revoke these freedoms as long as you follow the license terms.

UNDER THE FOLLOWING TERMS:

  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others
    from doing anything the license permits.

NOTICES:

  • You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
  • No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.

Select a payment method