Hairy Cell Leukemia – Immunotargets And Ther...

Dual Roles Of Cancer Cell-expressed Immunoglobu...

Nanocarrier-based Immunotherapy In Cancer Mana...

β1,3-glucan Anticancer Efficacies And Synerg...

Interleukin-17 And Type 17 Helper T Cells In C...

0 votes
Metastatic Renal Cell Carcinoma: Update On Epidemiology, Genetics, And Therapeutic Modalities
Author: Angela Graves, Hannah Hessamodini, Germaine Wong, Wai H Lim
Publisher: Derivative Works
18 pages
One time payment: €0.00
Required subscription: Free
Type of publication: Article
ISBN/ISSN: 2253-1556
DOI: 102147/31426
Follow this publisher

Share this publication:


Abstract: The treatment of advanced renal cell carcinoma (RCC) remains a major therapeutic challenge for clinicians. Despite advances in the understanding of the immunobiology of RCC and the availability of several novel targeted agents, there has been little improvement in the survival of patients with metastatic RCC. This review will focus on the recent understanding of risk factors and treatment options and outcomes of metastatic RCC, in particular, targeted therapeutic agents that inhibit vascular endothelial growth factor and mammalian target of rapamycin pathways. Prospective studies are required to determine whether sequential targeted therapy will further improve progression-free survival in RCC. Ongoing research to develop novel agents with better tolerability and enhanced efficacy in the treatment of metastatic RCC is required.

About the publisher:

We are a publishing house devoted to reuse CC-BY licensed published materials.


Using CC-BY licenses:


  • Adapt — remix, transform, and build upon the material
  • for any purpose, even commercially.
  • The licensor cannot revoke these freedoms as long as you follow the license terms.


  • No additional restrictions — You may not apply legal terms or technological measures that legally restrict others
    from doing anything the license permits.


  • You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation.
  • No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.

Select a payment method