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Hematological And Metabolically Aspects Of Laboratory Medicine -3-th Edition In New Review-
Author: Aurelian Udristioiu
Publisher: Emergency County Hospital TARGU-JIU
121 pages
One time payment: €148.80
Required subscription: Academic
Type of publication: Book
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The medical book, "Hematological and Metabolical Aspects of Laboratory Medicine", 3-nd edition, continues the analysis of  hematologic and metabolic aspects of the 3-nd  edition, in the context of international fundamental research. The volume is again successful Romanian medical school in abroad, and through this book brings a substantial contribution of Romanian medicine to universal medicine. It is not possible in this review, limited inevitably to be analyzed numerous data presented in the 15 chapters, but we emphasize the following:

- "Energy levels of the metabolic pathways in malignant B and T lymphocytes in Review" ,the chapter presents the latest evidence from the literature on cellular metabolites that may be oncogenic by modifying cell signaling and blocking cellular differentiation. Advances in cancer metabolism research in the last decade have increased our understanding on aerobic glycolysis, anaerobic and other metabolic changes that are associated with cell growth and proliferation.

Blocking apoptosis in malignant diseases may be due to the high concentration of ATP from anaerobic metabolism. Energy difference between anaerobic ATP B and T lymphocytes in peripheral blood samples from hematopoietic malignancies measured by bioluminescence was 2.68 μM ATP, a value that appears as an energy transfer between normal B cells and T cells. The energy level can initiate the process of carcinogenesis by suppressing the activity of anti-oncogene proteins.

    It is concluded that anabolic metabolism in B and T cells in hematological malignancies are under complex regulatory control, directed by receptors on the cell membrane associated with an increase in signal transduction in cells transformed into malignancy.

-The research paper " Endogenous effects of alcohol on liver function "  it sends a signal to the population as grim statistics that mortality from alcoholic liver disease in recent years has been higher than the of several major forms of cancer such as breast, colon and prostate .

   An international AASLD / ACG 2010 national guidance on the treatment of severe alcoholic hepatitis is proposed to be necessary in all treatment centers for liver disease due to chronic alcoholism.

-In the chapter " Drugs -induced hemolytic anemia " is presented a case that the best illustrates the cases of laboratory with drug-induced hemolytic anemia ( DIHA ) which are  rarely discovered,  and for this a specialized laboratory is often required to be performed with optimal serological tests to confirm the diagnosis. Some of the mechanisms involved in DIHA are controversially.

Unfortunately, most drugs that cause severe intravascular hemolysis, anemia, renal failure, disseminated intravascular coagulation times and even death, may have different mechanisms and typically involves drug addiction drug antibodies that trigger activity in serum total complement became the context of autoimmune hemolytic anemia.

   The following chapters convince the readers that this issues is addressed to medical personal for all specialties which can find the ideas on physiology, pathophysiology in the light of current concepts and modern principles.

   Interests of doctors in all specialties , medical students , staff working in clinical laboratories from 21 countries on five continents where the book is posted on sites, is based on the fact that this paper constitutes a large volume of data, experiences, clinical and laboratory research in a systematic and logical display. The new volume of para-clinical specialty rests on a solid scientific information , rigorously confronted with the author's own experience gained in basic medical education in the country and abroad.

About the publisher:

- My Book written in Clinical Laboratory Medicine, “ Hematological and Metabolical Aspects from Laboratory Medicine” , confirm the aria of my interest in discovery of carcinogenesis mechanisms, especially in onco-haematology field, Leukemia.


Also, my new e-Book: e-BOOK: Hematological and Metabolical Aspects of Laboratory Medicine (Hematological and Metabolical Aspects from Laboratory Medicine) ( Second Edition ) [Large Print] [Paperback].

Publisher: Aurelian Udristioiu, 2 edition (September 9, 2013) Full Color on White paper, 122 pages. ISBN-13: 978-1492186816 (CreateSpace-Assigned) ISBN-10: 1492186813, BISAC: Medical / Laboratory Medicine, USA. Sold by   

Please, see the Blog of my Medical Book :   




1. Udristioiu A. The Assessment of Uncertainty in Measurement of Cholesterol; A Model of Calculation. Biophysical Journal; Volume 96, Issue 3, Supplement 1, February 2009; Page 504a.

2. Udristioiu A, Florescu Cristina, Popescu Manuela Andrei. “High Concentration of anaerobic ATP implicated in aborted apoptosis from CLL”. LabMedicine, American Journal of Clinical Pathology-ASCP, Manuscript 09-08-LM-S-SCI-0122R1, Published in 04-05/2010.

3. Aurelian Udristioiu. First Hematological Signal of Latent Anemia to Aging Population. Nature Publishing Group. Advance Search 0.1038 npre 2009.3285.1. Creative Common Attribution 3.0 License, accepted for the work online posted.

4. Udristioiu A, Cojocaru M, Florescu C. Screening Tests for Latent Anemia in Hospitalized Adults Over 65.   LabMedicine, American Journal of Clinical Pathology-ASCP, Manuscript  09-11-LM-S-SCI-0156.R1,  Published  in 07-05/2010.USA American Journal of Clinical Pathology p-ISSN: 0002-9173 ICV 38.53 LabMedicine ; Ascp Press) , Impact Factor ISI, IF = 2.853 , 18 Index Copernicus Journals Master List 2006.


1 University of Medicine and Pharmacy “Carol Davila, Faculty of Pharmacy, Department of Microbiology, Traian Vuia 6, Sect. 2, 020956,Bucharest, Romania. 6“Stefan S. Nicolau” Virology Institute, Bucharest, Romania. FARMACIA 2010; (57); 3: 420-427 IMPACT FACTOR ISI THOMSON 0.144 .

6. Moleular Biological  Tchiniques  user for identification  of Candida SPP. MANUELA-ANDA RADU-POPESCU1*, SILVIA DUMITRIU2, SIMONA ENACHE-SOARE3,  AURELIAN UDRISTOIU4. 1 University of Medicine and Pharmacy “Carol Davila, Faculty of Pharmacy. FARMACIA 2010; (58); 4: 422-429

7. Udristioiu A. Role of Mg2+ ion as cofactor ATP in assurance of energetic environment cells( Abstract). Magnesium Research 2011; 24 (1): 22-6.

8. -Aurelian Udristioiu, Radu G. Iliescu, Cristina Popescu. Variability of bilirubin values in serum samples with high triglycerides; interference or congenital liver syndromes. J Biosci Tech Volume 2, Issue 4 (JULY 2011).

9. Aurelian Udristioiu¹*,Radu G. Iliescu², Lucian Udristioiu¹ and Manole Cojocaru. A new approach of abnormal apoptosis as a cause of autoimmunity and malignancy. Biotechnology and Molecular Biology Review Vol. 6(8), pp. 166-171, November 2011 . Available online at <>

10. Aurelian Udristioiu, Cristina Popescu, Manole Cojocaru, Sorina Comisel, Valentina Uscatescu. Relation between LDH and Mg as Factors of Interest in the Monitoring and Prognoses of Cancer. Journal of Bioanalysis & Biomedicine. Ref.:  Ms. No. JBABM-11-48R1 accepted on Jan 27, 2012

11. UDRISTIOIU A. Florescu C, Popescu C, Cojocaru M "Significance of Neutrophil Alkaline Phosphatase versus Isoenzymes ALP in Acute or Chronic Diseases,"accepted for publication in LabMedicine, LabMedicine Manuscript 11-03-LM-U-MR-0052.R2/11/12/2011.

12. Aurelian Udristioiu¹, Radu Iliescu ², Manole Cojocaru³. Errors in Counting Platelets in Hemodialysis Patients by Use of Optical Microscopy. Review of Applied Physics (RAP) Volume 2 Issue 1, March 2013; p: 17-22

13. Aurelian Udristioiu¹, Radu Iliescu ², Manole Cojocaru³. Energetic Levels of Metabolic Pathways in Malignant B and T Cells Mini-Review. Advances in Chemical Science Volume 2 Issue 4, December 2013; 2; 90-95

14. Aurelian Udristioiu¹, Manole Cojocaru² Hemolytic Anemia Drugs Induced by Antihypertensive Agents: A case of Laboratory. 13 Scholars Journal of Medical Case Reports ISSN 2347- 6559. Sch J Med Case Rep 2013; 1(1):8-11

15. Aurelian Udristioiu1*, Radu G. Iliescu2, Manole Cojoraru Molecular mechanisms of bone reconstruction in new dental implant technology. Integrated Journal of British. Volume 1 2014 Issue 1(5-6), pg: 1-7; IJBRITISH.


1.Aurelian Udristioiu. Cicloergometrul si Sanatatea. Ed. Medicala 1990, Bucuresti. ISBN: 973-39-01105-9; Formatul 16/10 x 100; Nr pagini: 78.

2.Aurelian Udristioiu. “Bioenergetica Celulara si Maligna” Ed. Academica Brancusi 2002, Targu Jiu, Bun de tipar, Bucuresti, Tipografia Everest 2001; ISBN 973 85342-6-7; Formatul 16/14 x 100; Nr. Pagini: 307.

3. Aurelian Udristioiu, Manole Cojocaru, Radu Iliescu., Hematological and Metabolic Aspects from Laboratory Medicine" (ISBN 978-3-8473-0775-4). LAP LAMBERT Academic Publishing GmbH & Co. KG Heinrich-Böcking-Str. 6-8 , 66121, Saarbrücken, Germany, 2012.

4. Book title: Renal Diseases / Book 2 (ISBN 979-953-307-704-7). Chapter title: Variability of Biological Parameters in Blood Samples between Two Consecutive Schedules of Hemodyalsis

Authors: Aurelian Udristioiu, Manole Cojocaru, Victor Dumitrascu, Daliborca Cristina Vlad, Alexandra Dana Maria Panait and Radu Iliescu, Publishing Group 2011., Volume 2, Issue 4 (JULY 2011)

5. e-BOOK: Hematological and Metabolical Aspects of Laboratory Medicine (Hematological and Metabolical Aspects from Laboratory Medicine) ( Second Edition ) [Large Print] [Paperback].


Publisher: Aurelian Udristioiu, 2 edition (September 9, 2013) Full Color on White paper, 122 pages. ISBN-13: 978-1492186816 (CreateSpace-Assigned) ISBN-10: 1492186813, BISAC: Medical / Laboratory Medicine, USA. Sold by  

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